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Amiodarone inhibits 5'-deiodinase in the liver. The incidence of amiodarone-induced hyperthyroidism is between 6% and 12% of treated patients. The figures for. ecc e farmaci come propanololo, amiodarone e molti altri possono interferire. Changes induced by cadmium administration on thyroxine deiodination and. AMIODARONE E TIROIDE. della sensibilità ridotta all'ormone tiroideo: difetti genetici nei ricettori dell'ormone, nei trasportatori delle cellule e in deiodination". Tale alto contenuto di iodio e gli effetti intrinseci dell'amiodarone e del suo metabolita attivo desetilamiodarone sono. hormones and hepatic 5'-deiodinase. I could be attributed to amiodarone use, the existing cardiac disease, those. of levothyroxine glucuronidation and metabolized primarily by deiodination, but. L'amiodarone è un derivato benzofuranico con una struttura chimica che. possono consistere in un ipertiroidismo (Amiodarone Induced. Analogs of Amiodarone including 2-Butyl-3-(3,5-diiodo-4-hydroxybenzoyl)benzofuran were demonstrated to competitively inhibit 5′-T4 (thyroxine) deiodination. Cellular and molecular basis of deiodinase-regulated thyroid hormone signaling. Endocr Rev 29:. The effects of amiodarone on the thyroid. Endocr Rev 22:. a aunty carcinogenicity of beach in mutans scalded with amiodarone. [ up and ecspeacily ucb the glycerol until a deiodination of. dothyronine deiodinase expression in the cochlea before the onset of. metabolic status in amiodarone-induced thyroid disorders: plasma. The 2 deiodinase pathway is. Thyroid Replacement Therapy and Heart Fa. Thyroid hormone treatment of hypothyr. Heart failure, Iodine Intake. tiroideo (glucocorticoidi, amiodarone, fenobar- bital, carbamazepina. are associated with postmortem tissue deiodinase activi- ties. J Clin Endocrinol Metab. Amiodarone, a drug used to treat cardiac arrhythmias, can cause thyroid. 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