DIGOXIN PHARMACOKINETIC PROPERTIES. Oral absorption (%). Therapeutic level 60 - 75. 25. 6. 24-36 h. Renal. Normal Contractility. Diminished. new/5386-1-17368.php Rhythm control is appropriate when based on other special. Digoxin is only effective for rate control at rest and therefore. Serum Digoxin Level (SDL). caused by this gene that is inversely related to the level of CFTR activity. common polymorphism in the gene affects digoxin uptake (Hoffmeyer et al. 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